The series will cover a comprehensive understanding of RESTful APIs, beginning with an introduction to the concept and its differentiation from other APIs. It will then delve into the best practices for designing RESTful APIs, featuring discussions on resource naming, HTTP methods, URI endpoints, and error handling. Practical implementation using Node.js and Express will be detailed, along with a focus on authentication, security, testing, and versioning strategies for RESTful APIs, providing a well-rounded understanding of the topic.